Recombinant Rabbit Monoclonal Antibody to MART-1 / Melan-A / MLANA (Melanoma Marker) (Clone : MLANA/1409R)
Selected Variant
12-1021-100
Size: 100 µg
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Product Specifications
Product Name Alternative
Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA
Gene Name
MLANA
Gene ID
2315
UniProt
Q16655
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human full-length MLANA protein
Target Antigen
MART-1 / Melan-A / MLANA (Melanoma Marker)
Clonality
Monoclonal
Clone
MLANA/1409R
Applications
WB, IHC
Purification
Purified Ab with BSA and Azide at 200ug/ml
Format
Purified
Components
200ug/mL of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Rabbit IgG
Price
Frequently Asked Questions
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