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Polyclonal Antibody to DPPA4

DPPA4 (Developmental pluripotency-associated 4) is a DNA binding SAP domain-containing protein. It is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. It is also mutated in some cancers. DPPA4 overexpression induces cell proliferation through genes related to regulation of G1/S transition. DPPA4 contains a functional HMG/POU cassette and behaves as a Sox2:Oct-3/4 target gene. Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis.

Product Specifications

Product Name Alternative

DPPA4

Gene Name

DPPA4

Gene ID

55211

UniProt

Q7L190

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant DPPA4 protein (amino acids 1-206) was used as the immunogen for this antibody.

Target Antigen

DPPA4

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-2 μg/mL

Isotype

Rabbit IgG

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