Polyclonal Antibody to DPPA4
DPPA4 (Developmental pluripotency-associated 4) is a DNA binding SAP domain-containing protein. It is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. It is also mutated in some cancers. DPPA4 overexpression induces cell proliferation through genes related to regulation of G1/S transition. DPPA4 contains a functional HMG/POU cassette and behaves as a Sox2:Oct-3/4 target gene. Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis.
Product Specifications
Product Name Alternative
DPPA4
Gene Name
DPPA4
Gene ID
55211
UniProt
Q7L190
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant DPPA4 protein (amino acids 1-206) was used as the immunogen for this antibody.
Target Antigen
DPPA4
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 1-2 μg/mL
Isotype
Rabbit IgG
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