Polyclonal Antibody to DLX3/distal-less homeobox 3
DLX3 (Distal-less homeobox 3) is a member of the large homeobox gene family of transcription factors. It plays a crucial role during embryonic development. DLX3 is expressed in a variety of tissues including placenta, skin, hair, teeth, and bone. Dlx3 interacts with Smad6, a member of a larger family of transcriptional regulators; generally regulate transforming growth factor beta/bone morphogenetic protein signaling. DLX3 supports the osteogenic differentiation in DFCs (Dental follicle cells) via a positive feedback loop with the bone morghogenetic protein (BMP) 2.
Product Specifications
Product Name Alternative
DLX3
Gene Name
DLX3
Gene ID
1747
UniProt
O60479
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant DLX3 protein (amino acids 93-282) was used as the immunogen for this antibody.
Target Antigen
DLX3/distal-less homeobox 3
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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