Polyclonal Antibody to NKX2-5
Cardiac-specific Nkx2-5 is a member of the NK2 family of homeodomain-containing transcription factors, and its expression and functions overlap with those of GATA4, GATA5, and GATA6 during cardiovascular genesis, especially in the regulation of target gene expression synergistically with GATA4, which justifies screening for Nkx2-5 as a prime candidate gene for idiopathic AF (Atrial Fibrillation) . NKX2-5 plays an important role in heart formation and development. Moreover, NKX2-5 not only individually acts in transcriptional regulation, but also interacts with other transcription factors in the early stage of cardiac development.
Product Specifications
Product Name Alternative
NKX2-5||CSX||NKX2.5||NKX2E
Gene Name
NKX2-5
Gene ID
1482
UniProt
P52952
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant NKX2-5 protein (amino acids 102-324) was used as the immunogen for this antibody.
Target Antigen
NKX2-5
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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