Polyclonal Antibody to SPZ1/TSP1
Spz1, a bHLH-zip protein, acts as a proto-oncogene regulated by a MAPK signaling pathway that can increase cell proliferation and tumorigenic activity as well as leading to primary tumor formation (15899793) . It is expressed specifically in the testis and epididymis (11165476) . Spz1 is a specific binding partner of the gamma2 catalytic subunit of Phosphatase-1c-gamma (PP1c-gamma) . The interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males.
Product Specifications
Product Name Alternative
SPZ1||TSP1
Gene Name
SPZ1
Gene ID
84654
UniProt
Q9BXG8
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant SPZ1/TSP1 protein (amino acids 10-213) was used as the immunogen for this antibody.
Target Antigen
SPZ1/TSP1
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 1-2 μg/mL
Isotype
Rabbit IgG
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