Polyclonal Antibody to HMGB3
HMGB3 (High Mobility Group-Box 3) belongs to the high mobility group box (HMG-box) subfamily. It has 99% homology with HMGB1 and HMGB2. This subfamily has a HMG-box, so it can regulate gene transcription by participating with formation of enhancesomes. The HMG-box subfamily also plays an important role in DNA replication, transcription, recombination and repair, etc. HMGB3 has been reported to have high expression in embryos and weak expression in adult tissues. HMGB3 is important in keeping the balance between self-renewal and differentiation status in mouse hematopoietic stem cells.
Product Specifications
Product Name Alternative
HMGB3||HMG2A||HMG4
Gene Name
HMGB3
Gene ID
3149
UniProt
O15347
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant HMGB3 protein was used as the immunogen for this antibody.
Target Antigen
HMGB3
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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