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Polyclonal Antibody to Twistnb

Twistnb is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. This protein contains 2 potential nuclear localization signals in the C terminus and shares 72% sequence identity with the mouse orthologs. Twistnb has highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.

Product Specifications

Product Name Alternative

TWISTNB

Gene Name

TWISTNB

Gene ID

221830

UniProt

Q3B726

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Twistnb protein (amino acids 28-257) was used as the immunogen for this antibody.

Target Antigen

Twistnb

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-2 μg/mL

Isotype

Rabbit IgG

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