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Polyclonal Antibody to PER1

PER1 (period circadian clock 1) is an important core clock protein and members of the circadian family of proteins, involved in the regulation of normal cell proliferations and physiological rhythms of human beings. It is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain and its function is to regulate physiological rhythms, cell cycle and DNA damage response of normal living subjects. Aberrant expressions and altered rhythms of PER1 are highly linked to the carcinogenesis and development of malignant tumors, such as prostate cancer, colon cancer, leukocythemia and breast cancer.

Product Specifications

Product Name Alternative

Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, KIAA0482, PER, RIGUI

Gene Name

PER1

Gene ID

5187

UniProt

O15534

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant PER1 protein (amino acids 1000-1200) was used as the immunogen for this antibody.

Target Antigen

PER1

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL

Isotype

Rabbit IgG

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