Polyclonal Antibody to PER1
PER1 (period circadian clock 1) is an important core clock protein and members of the circadian family of proteins, involved in the regulation of normal cell proliferations and physiological rhythms of human beings. It is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain and its function is to regulate physiological rhythms, cell cycle and DNA damage response of normal living subjects. Aberrant expressions and altered rhythms of PER1 are highly linked to the carcinogenesis and development of malignant tumors, such as prostate cancer, colon cancer, leukocythemia and breast cancer.
Product Specifications
Product Name Alternative
Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, KIAA0482, PER, RIGUI
Gene Name
PER1
Gene ID
5187
UniProt
O15534
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant PER1 protein (amino acids 1000-1200) was used as the immunogen for this antibody.
Target Antigen
PER1
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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