Polyclonal Antibody to S1P3 receptor, Edg-3
S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury) . S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.
Product Specifications
Product Name Alternative
S1PR3||EDG3
Gene Name
S1PR3
Gene ID
1903
UniProt
Q99500
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody.
Target Antigen
S1P3 receptor, Edg-3
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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