Polyclonal Antibody to Formin-like protein 2
Formin-like protein 2/FHOD1 (formin homology 2 domain containing 1) acts as a capping and bundling protein. In cells, active FHOD1 stimulates the formation of ventral stress fibers. FHOD1 is mainly located at the intercalated disc, the special type of cell-cell contact between cardiomyocytes (25125170) .FHOD1 promotes the formation of short actin filaments and transiently associates with transverse arcs, thus providing tight temporal and spatial control of the formation and turnover of transverse arcs into mature ventral stress fibers during dynamic cell behavior (24481812) .
Product Specifications
Product Name Alternative
Formin homology 2 domain-containing protein 2, FHOD2, KIAA1902
Gene Name
FMNL2
Gene ID
114793
UniProt
Q96PY5
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant Formin-like protein 2 protein (amino acids 1-321) was used as the immunogen for this antibody.
Target Antigen
Formin-like protein 2
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG
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