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Polyclonal Antibody to CD133/Prominin-1

CD133/Prominin-1 is a pentaspan transmembrane protein that has been frequently used as a biomarker for cancer stem cells, although its biological function is unclear. CD133 is not restricted to somatic stem cells and cancer stem cells. It is expressed in differentiated epithelial cells in various organs. Due to the highly restricted expression of CD133 family molecules on plasma membrane protrusions of epithelial and other cell types, in association with membrane cholesterol, a role in the organization of plasma membrane topology has also recently been assigned to this family.

Product Specifications

Product Name Alternative

PROM1||PROML1||MSTP061

Gene Name

PROM1

Gene ID

8842

UniProt

O43490

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant CD133 protein (amino acids 230-430) was used as the immunogen for this antibody.

Target Antigen

CD133/Prominin-1

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-2μg/mL

Isotype

Rabbit IgG

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