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Polyclonal Antibody to Dach1

DACH1, originally discovered in drosophila eye development, is an essential member of RDGN (Retinal Determination Gene Network) . This protein behaves as a tumor suppressor, and its expression is reduced in several cancers. The ectopic expression of DACH1 inhibits cellular proliferation in vitro and tumor growth in vivo. DACH1 is richly expressed in embryonal kidney cells and adult kidney tissues, but dramatically decreases in renal cancer cells.

Product Specifications

Product Name Alternative

DACH1||DACH

Gene Name

DACH1

Gene ID

1602

UniProt

Q9UI36

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Dach1 protein (amino acids 300-550) was used as the immunogen for this antibody.

Target Antigen

Dach1

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4μg/mL

Isotype

Rabbit IgG

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