Polyclonal Antibody to Dach1
DACH1, originally discovered in drosophila eye development, is an essential member of RDGN (Retinal Determination Gene Network) . This protein behaves as a tumor suppressor, and its expression is reduced in several cancers. The ectopic expression of DACH1 inhibits cellular proliferation in vitro and tumor growth in vivo. DACH1 is richly expressed in embryonal kidney cells and adult kidney tissues, but dramatically decreases in renal cancer cells.
Product Specifications
Product Name Alternative
DACH1||DACH
Gene Name
DACH1
Gene ID
1602
UniProt
Q9UI36
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant Dach1 protein (amino acids 300-550) was used as the immunogen for this antibody.
Target Antigen
Dach1
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG
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