Polyclonal Antibody to ASAP2
ASAP2 (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2) or Development and differentiation-enhancing factor 2 (DDEF2) or Paxillin-associated protein with ARF GAP activity 3 (PAG3) is a multidomain protein containing two ANK repeats, one Arf-GAP domain, one PH domain and one SH3 domain. ASAP2 has two isoforms: PAPalpha and PAPbeta (111 and 106 kDa respectively) and both the isoforms are generally located in Golgi plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2) . ASAP2 regulates ARF-mediated vesicle budding when vesicular transport. ASAP2 has high level of expression in brain, kidney, and heart.
Product Specifications
Product Name Alternative
ASAP2||DDEF2||KIAA0400
Gene Name
ASAP2
Gene ID
8853
UniProt
O43150
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant ASAP2 protein (amino acids 500-760) was used as the immunogen for this antibody.
Target Antigen
ASAP2
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG
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