Polyclonal Antibody to TIP60
TIP60 (60 kDa Tat-interactive protein) alternatively called as Lysine acetyltransferase 5 (KAT5) or Histone acetyltransferase KAT5 is a member of MYST protein family with four isoforms (58, 53, 61 and 56 kDa) . TIP60 plays important roles in regulating chromatin remodeling, transcription, DNA repair and apoptosis. TIP60 causes transcription activation by acetylating nucleosomal histones H4 and H2A. Mutations at gene level are associated with diseases like HIV-1, and Kaposis sarcoma. TIP60 is mainly expressed in brain tissue.
Product Specifications
Product Name Alternative
KAT5||HTATIP||TIP60
Gene Name
KAT5
Gene ID
10524
UniProt
Q92993
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant TIP60 protein (amino acids 300-500) was used as the immunogen for this antibody.
Target Antigen
TIP60
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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