Polyclonal Antibody to CRHR2
CRHR2 (CRF2R, CRH2R) (corticotropin releasing hormone receptor 2) belongs to the G-protein coupled receptor 2 family. This receptor has high affinity for corticotropin releasing hormone (CRH) and may also bind to CRH-related peptides, such as, urocortin. The human CRHR2 gene contains 12 exons. Three major functional isoforms have been reported: alpha, beta and gamma encoded by transcripts with alternative first exons which differ from each other by signal sequence and extra-cellular domain. CRH is synthesized in the hypothalamus and plays an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge. CRHR2 has high expression in brain, caudate nucleus, cerebrum, colon, endometrium, etc.
Product Specifications
Product Name Alternative
CRHR2||CRF2R||CRH2R
Gene Name
CRHR2
Gene ID
1395
UniProt
Q13324
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant CRHR2 protein (amino acids 1-200) was used as the immunogen for this antibody.
Target Antigen
CRHR2
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 0.5-2.0μg/mL
Isotype
Rabbit IgG
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