Polyclonal Antibody to TRH-R
TRH-R (Thyrotropin-releasing hormone (TRH) receptors are Gq/11-protein-coupled receptors) is a member of G-protein coupled receptor 1 family. This is a thyrotropin-releasing hormone receptor. When it binds to TRH, it activates the inositol phospholipid-calcium-protein kinase C transduction pathway. TRH-R also interacts with ACP2acid phosphatase 2. Its expression found mainly in cerebrum, testis during developmental stage. Literature suggests that endogenous TRH and TRH receptor play an important role of a neurotransmission modulation in the brain to control emotional and mental functions.
Product Specifications
Product Name Alternative
TRHR
Gene Name
TRHR
Gene ID
7201
UniProt
P34981
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant TRH-R protein (amino acids 180- 398) was used as the immunogen for this antibody.
Target Antigen
TRH-R
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 1-3μg/mL
Isotype
Rabbit IgG
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