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Polyclonal Antibody to Chaperonin

HSPD1 (heat shock 60 kDa protein 1 (chaperonin) ) is a member of the chaperonin family of proteins. Chaperonin may function as a signaling molecule in the innate immune system and is essential for the folding and assembly of newly imported proteins in the mitochondria implicated in mitochondrial protein import and macromolecular assembly. Diseases associated with HSPD1 include spastic paraplegia 13. It exists in two isoforms comprised of 573 amino acids. Chaperonin is expressed in adipose tissue, adrenal cortex, adrenal gland, blood and brain.

Product Specifications

Product Name Alternative

HSPD1||HSP60

Gene Name

HSPD1

Gene ID

3329

UniProt

P10809

Host

Rabbit

Reactivity

Mouse, Human

Immunogen

A partial length recombinant Chaperonin protein (amino acids 300-570) was used as the immunogen for this antibody.

Target Antigen

Chaperonin

Clonality

Polyclonal

Applications

IHC, WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-3 μg/mL, Immunohistochemical analysis: 5 μg/mL

Isotype

Rabbit IgG

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