Polyclonal Antibody to Exportin-4
Exportin-4 or XPO4 belongs to a large family of nucleoproteins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. Exportin-4 is a RanGTP-binding protein and functions as a receptor for nuclear export of EIF-5A and also may have a role as an adapter in RNA export. Exportin-4 has been reported to be involved in nuclear export of Smad3 and thereby regulation of Smad signaling. Diseases associated with XPO4 include pinguecula. This protein has ubiquitously expressed.
Product Specifications
Product Name Alternative
XPO4||KIAA1721
Gene Name
XPO4
Gene ID
64328
UniProt
Q9C0E2
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant Exportin-4 protein (amino acids 775-1,000) was used as the immunogen for this antibody.
Target Antigen
Exportin-4
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 1-3μg/mL
Isotype
Rabbit IgG
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