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Polyclonal Antibody to C5L2/GPCR77

C5a anaphylatoxin chemotactic receptor 2 (C5L2) encodes a G-protein coupled receptor 1, also known as C5L2, G protein-coupled receptor 77. C5L2 involved in the complement system of the innate immune response. It has high affinity and several receptors not only for C5a, desarginated C5a, and C3a, but also for desarginated C3a, the acylation-stimulating protein. Diseases associated with C5AR2 include artery diseases and sepsis. C5L2 expressed mainly on frontal cortex, hippocampus, hypothalamus, pons and liver.

Product Specifications

Product Name Alternative

C5AR2||C5L2||GPR77

Gene Name

C5AR2

Gene ID

27202

UniProt

Q9P296

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant C5L2/GPCR77 protein (amino acids 1-240) was used as the immunogen for this antibody.

Target Antigen

C5L2/GPCR77

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-2μg/mL

Isotype

Rabbit IgG

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