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Polyclonal Antibody to CLIM1/PDLIM1

PDLIM1 (PDZ and LIM Domain 1) belongs to the enigma protein family. It contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxy terminal. LIM domains are cysteine-rich double zinc fingers that are involved in protein-protein interactions. PDLIM1 has transcription coactivatior activity and it may play a role as an adapter to bring other LIM-interacting proteins to the cytoskeleton. This gene is found to be highly expressed in the heart and skeletal muscle and moderately expressed in the spleen. PDLIM1 consists of 329 amino acids and is associated with hyperacusis and supravalvular aortic stenosis diseases.

Product Specifications

Product Name Alternative

PDLIM1||CLIM1||CLP36

Gene Name

PDLIM1

Gene ID

9124

UniProt

O00151

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant CLIM1 protein (amino acids 116-329) was used as the immunogen for this antibody.

Target Antigen

CLIM1/PDLIM1

Clonality

Polyclonal

Applications

IHC, WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-3 μg/mL, Immunohistochemical analysis: 5 μg/mL

Isotype

Rabbit IgG

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