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Polyclonal Antibody to Cadherin-17

Cadherin-17 (CDH17), acts as a unique member of cadherin family mediating cell-cell adhesion, expresses exclusively in human intestinal and pancreatic ductal epithelial cells, which is not supposed to be found in healthy stomach. This protein is also called LI (Liver Intestine) cadherin or HPT-1 (Human Peptide Transporter-1) and is a structurally unique member of the cadherin superfamily. Whereas the so-called classic cadherins, such as E-, N- and P-cadherin, have five cadherin repeats within the extracellular domain, CDH17 consists of seven cadherin repeats.

Product Specifications

Product Name Alternative

CDH17

Gene Name

CDH17

Gene ID

1015

UniProt

Q12864

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Cadherin-17 protein (amino acids 238-446) was used as the immunogen for this antibody.

Target Antigen

Cadherin-17

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 1-2 μg/mL

Isotype

Rabbit IgG

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