Polyclonal Antibody to DKK1
DKK1 is a 68 kDa protein of the Dickkopf family. DKK1 is a secreted protein with two cysteine-rich domains which help in interaction with LRP5 and LRP6 thereby inhibiting the Wnt signaling pathway. DKK1 regulates embryonic development in vertebrates. DKK1 is over expressed in bone marrow and peripheral blood in patients with multiple myeloma. DKK1 is also associated with malignant myeloma. DKK1 is highly expressed in placenta.
Product Specifications
Product Name Alternative
DKK1||UNQ492/PRO1008
Gene Name
DKK1
Gene ID
22943
UniProt
O94907
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant DKK1 protein was used as the immunogen for this antibody.
Target Antigen
DKK1
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 4-6 μg/mL
Isotype
Rabbit IgG
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