Polyclonal Antibody to Histone H2A
Histone H2A is one of the five main histone proteins that is approximately 14 kDa protein consisting of 130 amino acid residues and present in the nucleosome in the form of H2A-H2B heterodimer. H2A is mainly composed of non-allelic variants and interestingly atypical variants, such as, MacroH2As, H2A.X, H2A-Bbd, differ considerably in size with H2A. H2A undergoes various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination, which occur in response to various stimuli and directly affect the accessibility of chromatin to transcription factors. This gene is mainly expressed on blood, brain, breast and it plays a significant role in the disease, riddle syndrome.
Product Specifications
Product Name Alternative
HIST1H2AB||H2AFM
Gene Name
HIST1H2AB
Gene ID
3012
UniProt
P04908
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant Histone H2A protein was used as the immunogen for this antibody.
Target Antigen
Histone H2A
Clonality
Polyclonal
Applications
IHC, WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL, Immunohistochemical analysis: 5 μg/mL
Isotype
Rabbit IgG
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