Polyclonal Antibody to DMAP1
DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene and consisting of 433 aminoacids. It is involved in transcription repression and activation. DMAP1 interacts with HDAC2 which provides a mechanism for histone deacetylation in heterochromatin following replication of DNA at late dismissal origins. DMAP1 can also repress transcription independently of histone deacetylase activity. It participates in the nuclear localization of URI1 and increases its transcriptional co-repressor activity. It is expressed in adipose tissue, adrenal gland, amniotic fluid, cerebellar cortex, hippocampus, liver, etc.
Product Specifications
Product Name Alternative
DMAP1||KIAA1425
Gene Name
DMAP1
Gene ID
55929
UniProt
Q9NPF5
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant DMAP1 protein (amino acids 140-462) was used as the immunogen for this antibody.
Target Antigen
DMAP1
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG
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