Polyclonal Antibody to LSD1
LSD1 or KDM1A (lysine (K) -specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.
Product Specifications
Product Name Alternative
KDM1A||AOF2||KDM1||KIAA0601||LSD1
Gene Name
KDM1A
Gene ID
23028
UniProt
O60341
Host
Rabbit
Reactivity
Mouse, Human
Immunogen
A partial length recombinant LSD1 protein (amino acids 97-328) was used as the immunogen for this antibody.
Target Antigen
LSD1
Clonality
Polyclonal
Applications
IHC, WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 0.5-2.0 μg/mL, Immunohistochemical analysis: 5 μg/mL
Isotype
Rabbit IgG
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