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Polyclonal Antibody to Cactin

CACTIN is a conserved protein, discovered as a novel interactor of Drosophila IkappaB protein Cactus. It is highly conserved during evolution and plays a key role in early embryonic development. It is characterized as a negative regulator of many different developmental processes, but only found to play an immune role in humans. CACTIN localizes to nuclear speckles and colocalizes with known splicing proteins. It binds to a putative component of the spliceosome, major role for CACTIN in splicing.

Product Specifications

Product Name Alternative

CACTIN||C19orf29

Gene Name

CACTIN

Gene ID

58509

UniProt

Q8WUQ7

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Cactin protein (amino acids 320-521) was used as the immunogen for this antibody.

Target Antigen

Cactin

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4μg/mL

Isotype

Rabbit IgG

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