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Polyclonal Antibody to UNC93B

Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level), antigen-presenting cells (high) and at lower level in kidney.

Product Specifications

Product Name Alternative

UNC93B1||UNC93||UNC93B

Gene Name

UNC93B1

Gene ID

81622

UniProt

Q9H1C4

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.

Target Antigen

UNC93B

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 4-6 μg/mL

Isotype

Rabbit IgG

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