Polyclonal Antibody to ST2

ST2V or ST2 is a member of the interleukin 1 receptor family. It acts as receptor for interleukin-33 (IL33) and its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6, followed by phosphorylation of MAPK3/ERK1. Diseases associated with ST2V are yellow fever and allergic conjunctivitis. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine and has four isoforms produced by alternate splicing.

Product Specifications

Product Name Alternative

IL1RL1||DER4||ST2||T1

Gene Name

IL1RL1

Gene ID

9173

UniProt

Q01638

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant ST2V protein (amino acids 150-300) was used as the immunogen for this antibody.

Target Antigen

ST2V or ST2

Clonality

Polyclonal

Applications

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL This antibody detects ~34 kDa band. The size corresponds to Isoform 2 (Uniprot ID-Q01638-2) of ST2, the right size is ~63 kDa.