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Polyclonal Antibody to APG4B

APG4B (autophagy related 4B, cysteine peptidase) belongs to autophagin protein family. APG4B splits the C-terminal amino acid of ATG8 family proteins, MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. It has 393 aminoacids recidues. It has 5 isoforms produced by alternative transcriptional splicing. APG4B is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas. It is a Cysteine protease needed for the cytoplasm to vacuole transport (Cvt) and autophagy. APG4B mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.

Product Specifications

Product Name Alternative

ATG4B||APG4B||AUTL1||KIAA0943

Gene Name

ATG4B

Gene ID

23192

UniProt

Q9Y4P1

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant APG4B protein (amino acids 1-300) was used as the immunogen for this antibody.

Target Antigen

APG4B

Clonality

Polyclonal

Applications

WB

Purification

Protein A Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 4-6 μg/mL

Isotype

Rabbit IgG

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