Polyclonal Antibody to DRAM
DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.
Product Specifications
Product Name Alternative
DRAM1||DRAM
Gene Name
DRAM1
Gene ID
55332
UniProt
Q8N682
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant DRAM protein (amino acids 1-230) was used as the immunogen for this antibody.
Target Antigen
DRAM
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 4-6μg/mL
Isotype
Rabbit IgG
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