Monoclonal Antibody to SARS-CoV-2 Nucleocapsid (Clone: ABM3F2.1C1)
The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.
Product Specifications
Gene Name
N
Gene ID
43740575
UniProt
P0DTC9
Host
Mouse
Immunogen
Full length recombinant SARS-CoV-2 nucleocapsid protein was used as the immunogen for this antibody.
Target Antigen
Nucleocapsid
Clonality
Monoclonal
Clone
ABM3F2.1C1
Applications
ELISA, WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Recommended dilutions: WB: 0.1-1 μg/mL, ELISA: 1 μg/mL. However, this need to be optimized based on the research applications.
Isotype
Mouse IgG2b, Kappa
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