Anti Glut-4 Monoclonal Antibody (Clone: ABM5D66)
The Glucose Transporter Glut-4 protein, also known SLC2A4 in human encodes a member of the solute carrier family 2, with a mass of 54,787 daltons, and has two identified isoforms. It is reported to contain sites of glycosylation. The Glut-4 protein serves as a facilitative glucose transporter, which is regulated by insulin. When there is no insulin present, this membrane protein remains within the cells of adipose tissue and muscle. However, within minutes of insulin stimulation, the protein is transported to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus and obesity. The Anti Glut-4 Monoclonal Antibody is a mouse monoclonal IgG1 kappa Glucose Transporter that is recommended for detecting Glut4 of mouse, rat, and human origin through WB, IP, IF, and IHC (P) .
Product Specifications
Product Name Alternative
Glucose transporter type 4, insulin-responsive, SLC2A4
Gene Name
SLC2A4
Gene ID
6517
UniProt
P14672
Host
Mouse
Reactivity
Human
Target Antigen
GLUT-4
Clonality
Monoclonal
Clone
ABM5D66
Applications
WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Recommended dilutions: WB:2-4 μg/mL. However, this need to be optimized based on the research applications.
Isotype
Mouse IgG1, Kappa
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