Rabbit Monoclonal Antibody to EpCAM (Clone: ABM53D8)
EpCAM (epithelial specific antigen) is an ~40 kDa transmembrane glycoprotein involved in a number of cellular processes including adhesion, proliferation, maintenance of stemness, migration and invasion. EpCAM is expressed on most, but not all, normal epithelia and their corresponding malignancies. Although the role of EpCAM expression in tumorigenesis remains to be fully elucidated, EpCAM may downregulate immunity and help tumors actively escape from immune surveillance.
Product Specifications
Product Name Alternative
EPCAM||GA733-2||M1S2||M4S1||MIC18||TACSTD1||TROP1
Gene Name
EPCAM
Gene ID
4072
UniProt
P16422
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant EpCam protein (amino acid 56-267) was used as immunogen for this antibody.
Target Antigen
EpCAM
Clonality
Monoclonal
Clone
ABM53D8
Applications
WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rabbit IgG
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