Monoclonal Antibody to FSH Receptor (Clone: ABM5D29)
FSH receptor is a member of the G protein coupled receptor family consisting of 9 introns and 10 exons and a promoter region and is located on chromosome 2p21. FSH receptor was shown to be expressed selectively on the luminal surface of tumor blood vessels. A general characteristic of the blood vessels that express the endothelial FSH receptor is that they are located at the periphery of the tumors. Many studies showed that FSH receptor polymorphisms at positions 307 and 680 may be even more relevant for clinical practice for the reasons of regulating the ovarian reaction to hormone, controlling ovarian hyperstimulation, changing the menstrual cycle, and causing POF (Premature Ovarian Failure) and PCOS (Polycystic Ovary Syndrome) .
Product Specifications
Product Name Alternative
Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor
Gene Name
FSHR
Gene ID
2492
UniProt
P23945
Host
Mouse
Reactivity
Human
Immunogen
A partial length recombinant protein (a.a 03-200) of FSH Receptor was used as the immunogen for this antibody.
Target Antigen
FSH Receptor
Clonality
Monoclonal
Clone
ABM5D29
Applications
FACS, WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
WB: 2-4 μg/mL, FACS: 0.5-1 μg/10^6
Isotype
Mouse IgG1, kappa
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