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Monoclonal antibody to FOXA1 (Clone: ABM4A82)

FoxA1 (forkhead box A1), also called HNF-3 alpha (hepatocyte nuclear factor 3 alpha) or TCF3A (transcription factor 3A) is a 473 amino acid (aa), 49 kDa (predicted) protein of the forkhead nuclear transcription factor family. Also known as hepatocyte nuclear factors, which are transcriptional activators for liver-specific transcripts such as albumin and transthyretin. The HNF3 family, including HNF3A, HNF3B, and HNF3G, are members of the forkhead class of DNA-binding proteins. It regulates transcription downstream of the estrogen receptor and other steroid hormone receptors.

Product Specifications

Product Name Alternative

FOXA1||HNF3A||TCF3A

Gene Name

FOXA1

Gene ID

3169

UniProt

P55317

Host

Mouse

Reactivity

Human

Immunogen

A partial length recombinant protein from C terminal portion of hFOXA1 was used as the immunogen for this antibody.

Target Antigen

FOXA1

Clonality

Monoclonal

Clone

ABM4A82

Applications

IHC, WB

Purification

Protein G Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL; Immunohistochemestry: 5-10 μg/mL

Isotype

Mouse IgG2b Kappa

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