Monoclonal Antibody to SOX11 (Clone: ABM45D9)
SOX11 (Sex determining region Y-box 11), located on chromosome 2p25, belong to the family of genes SOXC. It is a transcript factor involved in the embryonic neurogenesis and tissue remodeling, also participating in the control of cell proliferation. It is involved in gastrulation and in malignant diseases. It is expressed in foetal and neoplastic brain tissue, including gliomas (23619925) . SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs) . Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome.
Product Specifications
Product Name Alternative
SOX11
Gene Name
SOX11
Gene ID
6664
UniProt
P35716
Host
Mouse
Reactivity
Mouse, Human
Immunogen
A partial length recombinant Sox11 protein (amino acids 23-236) was used as the immunogen for this antibody.
Target Antigen
SOX11
Clonality
Monoclonal
Clone
ABM45D9
Applications
WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 0.5-1 μg/mL
Isotype
Mouse IgG2b Kappa
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