Monoclonal Antibody to TOX-3 (Clone: ABM44A1)
TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI) .
Product Specifications
Product Name Alternative
TOX3||CAGF9||TNRC9
Gene Name
TOX3
Gene ID
27324
UniProt
O15405
Host
Mouse
Reactivity
Human
Immunogen
A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody
Target Antigen
TOX-3
Clonality
Monoclonal
Clone
ABM44A1
Applications
IHC, WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL, Immunohistochemical analysis: 5 μg/mL
Isotype
Mouse IgG1 Kappa
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