Monoclonal Antibody to EpCAM (Clone: VU-1D9)
EpCAM (epithelial specific antigen) is an ~40 kDa transmembrane glycoprotein involved in a number of cellular processes including adhesion, proliferation, maintenance of stemness, migration and invasion. EpCAM is expressed on most, but not all, normal epithelia and their corresponding malignancies. Although the role of EpCAM expression in tumorigenesis remains to be fully elucidated, EpCAM may downregulate immunity and help tumors actively escape from immune surveillance.
Product Specifications
Product Name Alternative
EPCAM||GA733-2||M1S2||M4S1||MIC18||TACSTD1||TROP1
Gene Name
EPCAM
Gene ID
4072
UniProt
P16422
Host
Mouse
Reactivity
Human
Immunogen
Target Antigen
EpCAM
Clonality
Monoclonal
Clone
VU-1D9
Applications
IHC, FACS, WB
Purification
Protein G Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Immunohistochemical analysis: 1:100-1:200; Flowcytometry analysis: 0.2-0.5 μg/10^6 cells, Western blot analysis: 4-6 μg/mL
Isotype
Mouse IgG1 Kappa
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