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Monoclonal Antibody to Ikkb (Clone: ABM10E6)

IKKB also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein which is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene. IKKB causes dissociation of the inhibitor and activation of NF-kappa-B which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Higher expression of this protein is found in liver, kidney and spleen.

Product Specifications

Product Name Alternative

IKBKB||IKKB

Gene Name

IKBKB

Gene ID

3551

UniProt

O14920

Host

Mouse

Reactivity

Human

Immunogen

Full length recombinant Ikkb protein was used as the immunogen for this antibody.

Target Antigen

IKKb

Clonality

Monoclonal

Clone

ABM10E6

Applications

WB

Purification

Protein G Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL

Isotype

Mouse IgG1 Kappa

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