Monoclonal antibody to CD247/CD3 Zeta (TCR¶, CD3¶) (Clone: 6B10.2)
The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCR heterodimer. The disulfide-linked TCR zeta homodimers transmit signals following TCR ligation. Loss of TCR zeta expression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.
Product Specifications
Product Name Alternative
T-cell receptor T3 zeta chain, CD247, CD3zeta, CD3Z, T3Z, TCRZ
Gene Name
CD247
Gene ID
919
UniProt
P20963
Host
Mouse
Reactivity
Human
Immunogen
Human TCR zeta chain aa38-54
Target Antigen
CD247
Clonality
Monoclonal
Clone
6B10.2
Applications
WB
Purification
Affinity chromatography
Format
Purified
Components
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage Conditions
The antibody solution should be stored undiluted between 2°C and 8°C.
Isotype
Mouse IgG1 Kappa
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