Monoclonal Antibody to human C9 neoepitope (Clone: aE11)
The TCC consisting of C5b, C6, C7, C8, and C9, contains neoantigens that are absent from the individual native components. Neoantigens are present both in the MAC and the fluid-phase (SC5b-9) complex. This membrane attack complex forms channels in target cell membranes which is leading by osmotic leakag to cell lysis. The complexes contain neoantigens that are absent from the individual native components from which they are formed and DIA 011-01 is directed against a neoepitope exposed on C9 when incorporated into the TCC.
Product Specifications
Product Name Alternative
Complement component C9, Complement component C9a/C9b
Gene Name
C9
Gene ID
735
UniProt
P02748
Host
Mouse
Reactivity
Human
Immunogen
Full length protein corresponding to Human C9 neoepitope was used as thge immunogen for this antibody.
Target Antigen
C9 neoepitope
Clonality
Monoclonal
Clone
AE11
Applications
ELISA, ICC/IF, IHC, FACS
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles
Applications Notes
Immunohistochemical analysis: 1:5-1:10 dilution
Isotype
Mouse IgG2a, kappa
Conjugate
Unconjugated
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
