Monoclonal Antibody to CD8 (Clone: RPAT8)
CD8 membrane glycoprotein that is expressed on cytotoxic T-cells where it interacts with MHC class I processed antigens. CD8 also regulates T-cell activation and differention. CD8 has two isoforms (25 and 21 kDa) CD8 can function either as a homodimer (two alpha chains) or as a heterodimer (one alpha and one beta chain) . CD8 is highly expressed in T lymphocyte, peripheral blood T-lymphocytes, thymus, spleen and lymphocyte.
Product Specifications
Product Name Alternative
CD8A||MAL
Gene Name
CD8A
Gene ID
925
UniProt
P01732
Host
Mouse
Reactivity
Human
Immunogen
Full length CD8a-alpha chain was used as the immunogen for this antibody.
Target Antigen
CD8
Clonality
Monoclonal
Clone
RPAT8
Applications
FACS
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
FACS analysis: 0.5 μg/10^6 cells
Isotype
Mouse IgG1 Kappa
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