Monoclonal Antibody to CD4 (Clone: RPA-T4)
CD4 is a 51 kDa membrane glycoprotein that is expressed on subsets of thymocytes and mature T lymphocytes where it works as co-receptor for T-cell receptor and interacts with MHC Class II processed antigens. CD4 is also expressed on surface of monocytes, macrophages and dendritic cells. CD4 also regulates T-cell activation and differention. CD4 is identified as the cellular receptor for HIV and several other viral infections. CD4 is highly expressed in thymus, spleen and lymphocyte.
Product Specifications
Product Name Alternative
CD4
Gene Name
CD4
Gene ID
920
UniProt
P01730
Host
Mouse
Reactivity
Human
Immunogen
PHA-stimulated human PBMC.
Target Antigen
CD4
Clonality
Monoclonal
Clone
RPA-T4
Applications
FACS
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
FACS analysis: 0.5 μg/10^6 cells
Isotype
Mouse IgG1 Kappa
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