Monoclonal Antibody to RunX3 (Clone: ABM28D1)
Runt-related transcription factor 3 (Runx3) forms a heterodimer of alpha and beta subunit and binds to the core of the promoter to regulate the transcription. It plays an important role in tumor suppressor and the gene is frequently deleted or transcriptionally silenced during tumor development. It has multiple isoforms coded by multiple transcript variances.
Product Specifications
Product Name Alternative
RUNX3||AML2||CBFA3||PEBP2A3
Gene Name
RUNX3
Gene ID
864
UniProt
Q13761
Host
Mouse
Reactivity
Human
Immunogen
A partial length recombinant Runx3 protein (amino acids 100-320) was used as the immunogen for this antibody.
Target Antigen
Runx3
Clonality
Monoclonal
Clone
ABM28D1
Applications
FACS, WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL, Flowcytometry analysis: 0.5-1 μg/10^6 Cells
Isotype
Mouse IgG2b Kappa
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