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Monoclonal Antibody to RunX3 (Clone: ABM28D1)

Runt-related transcription factor 3 (Runx3) forms a heterodimer of alpha and beta subunit and binds to the core of the promoter to regulate the transcription. It plays an important role in tumor suppressor and the gene is frequently deleted or transcriptionally silenced during tumor development. It has multiple isoforms coded by multiple transcript variances.

Product Specifications

Product Name Alternative

RUNX3||AML2||CBFA3||PEBP2A3

Gene Name

RUNX3

Gene ID

864

UniProt

Q13761

Host

Mouse

Reactivity

Human

Immunogen

A partial length recombinant Runx3 protein (amino acids 100-320) was used as the immunogen for this antibody.

Target Antigen

Runx3

Clonality

Monoclonal

Clone

ABM28D1

Applications

FACS, WB

Purification

Protein G Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL, Flowcytometry analysis: 0.5-1 μg/10^6 Cells

Isotype

Mouse IgG2b Kappa

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