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Monoclonal Antibody to IL-17RE (Clone: ABM2G70)

IL-17RE (Interleukin 17 receptor E) is an orphan receptor of the IL-17 receptor family. The members of this receptor family play a critical role in inflammatory responses and contribute to the pathology of many autoimmune diseases. IL-17RE is a receptor specific to IL-17C preferentially expressed on tissue epithelial cells and regulates early innate immunity to intestinal pathogens by signaling to downstream components of the mitogen activated protein kinase (MAPK) pathway.

Product Specifications

Product Name Alternative

IL17RE||UNQ3056/PRO9877

Gene Name

IL17RE

Gene ID

132014

UniProt

Q8NFR9

Host

Mouse

Reactivity

Mouse, Human

Immunogen

A partial length recombinant human IL-17RE protein (amino acids 50-268) was used as the immunogen for this antibody.

Target Antigen

IL-17RE

Clonality

Monoclonal

Clone

ABM2G70

Applications

FACS, WB

Purification

Protein G Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL, Flowcytometric analysis- 2-4 μg/10^6 Cells

Isotype

Mouse IgG2b Kappa

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