Monoclonal Antibody to Mouse EBI3 (Clone: ABM2C40)
Epstein-Barr Virus Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.
Product Specifications
Product Name Alternative
Ebi3||Il27b
Gene Name
Ebi3
Gene ID
50498
UniProt
O35228
Host
Rat
Reactivity
Mouse
Immunogen
A full length recombinant mEBI3 protein was used as the immunogen for this antibody.
Target Antigen
EBI3 Mouse
Clonality
Monoclonal
Clone
ABM2C40
Applications
WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL
Isotype
Rat IgG2b Kappa
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