Monoclonal Antibody to Dectin-2 (Clone: ABM2H28)
Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca (2+) -dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
Product Specifications
Product Name Alternative
CLEC6A||CLECSF10||DECTIN2
Gene Name
CLEC6A
Gene ID
93978
UniProt
Q6EIG7
Host
Mouse
Reactivity
Mouse, Human
Immunogen
A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.
Target Antigen
Dectin-2
Clonality
Monoclonal
Clone
ABM2H28
Applications
IHC, FACS, WB
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL, FACS analysis: 0.5 μg/10^6 cells, Immunohistochemical analysis: 5 μg/mL
Isotype
Mouse IgG2a Kappa
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PE Linked Polyclonal Antibody to Glutathione S Transferase Pi (GSTp)
PE Linked Polyclonal Antibody to Glutathione S Transferase Pi (GSTp)
PE Linked Polyclonal Antibody to Glutathione S Transferase Pi (GSTp)
PE Linked Polyclonal Antibody to Glutathione S Transferase Pi (GSTp)